PATHOPHYSIOLOGY OF MYELODYSPLASTIC SYNDROMES

Pathophysiology of Myelodysplastic Syndromes

Ineffective hematopoiesis is the major characteristic of early myelodysplastic syndromes.Its pathophysiology relies on a diversity of mechanisms supported by genetic events that develop in aging hematopoietic stem cells.Deletion and mutations trigger epigenetic modifications, and co-transcriptional and post-transcriptional deregulations of gene exp

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Assessing the Status of Yazd Province Medical Emergency and Accident Management Center in Terms of Necessary Standards for Air Emergencies

Background: Air emergency medical services provide advanced medical care to patients and critically injured as soon as possible to reduce injuries and casualties.In this study, the status of the Medical Emergency and Accident Management Center in Yazd Province in terms of the necessary standards for air emergencies was investigated and compared wit

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Innumeracy and incentives

The Ratio-Bias phenomenon, observed by psychologist Seymour Epstein and colleagues, is a systematic manifestation of irrationality.When offered a choice between two lotteries, individuals consistently choose the lottery with the greater number of potential successes, even when it offers a smaller probability of success.In the current study, we cond

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Plummeting costs of renewables - Are energy scenarios lagging?

Wind and solar energy play a pivotal role in deep decarbonization pathways for the future.However, energy scenario studies differ substantially in the contribution of these technologies, as the technology selection in models strongly depends on the choice of techno-economic parameters.In kt-swled45ps-4a-8csa-vdim-p this article, we systematically c

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